HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromo-4-(3-chlorophenyl)-2-methoxyquinoline → [4-(3-chloro-phenyl)-2-methoxy-quinolin-6-yl]-(6-methyl-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromo-4-(3-chlorophenyl)-2-methoxyquinoline | HCID 12016672 | — |
| Reactant | 2-methyl-5-(1-methyl-1H-imidazole-5-carbonyl)pyridine | HCID 22465447 | — |
| Product | [4-(3-chloro-phenyl)-2-methoxy-quinolin-6-yl]-(6-methyl-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanol | HCID 18404110 | 48% |
Reaction Steps
Following the same procedure as that described in Example 1E, 6-bromo-4-(3-chloro-phenyl)-2-methoxy-quinoline (0.200 g, 0.574 mmol) and (6-methyl-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanone (0.105 g, 0.522 mmol) generated 0.118 g (48% yield) of [4-(3-chloro-phenyl)-2-methoxy-quinolin-6-yl]-(6-methyl-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06388092B2 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-858b1677bc57472da0babc8a3eae32ad |
| Source note | uspto-grants-2002_05 |