HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1936525Generated: October 26, 2026
Acetaldehyde → 1-Methacryloyloxy-3,5-di(1-hydroxyethoxy)adamantane
https://huagongshe.com/reaction/1936525
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetaldehyde | HCID 177 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 3,5-Dihydroxy-1-adamantyl methacrylate | HCID 13007394 | — |
| Product | 1-Methacryloyloxy-3,5-di(1-hydroxyethoxy)adamantane | HCID 13007395 | — |
Reaction Steps
To 30 ml of tetrahydrofuran were added 5 mmol of 1-methacryloyloxy-3,5-dihydroxyadamantane, 15 mmol of acetoaldehyde, and 1 mmol of p-toluenesulfonic acid, and the mixture was stirred at 30° C. for 6 hours. The reaction mixture was condensed under acidic conditions and crystallized by adding to diethyl ether dropwise to give the object compound 1-methacryloyloxy-3,5-di(1-hydroxyethoxy)adamantane (acetal compound) represented by the following formula:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06391520B1 |
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| Source dataset | uspto-grants-2002_05 |
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| ORD ID | ord-3c1bf51523dc4542a571611b83e454b9 |
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| Source note | uspto-grants-2002_05 |
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