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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1936627Generated: October 30, 2026

HCID 15922606, compound → HCID 54160248, compound

https://huagongshe.com/reaction/1936627

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 15922606HCID 15922606—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 54160248HCID 54160248100.1%

Reaction Steps

To 10 ml of an ethanol solution of 340.4 mg (0.94 mmol) of 1-benzyloxycarbonyl-3-(cis-2-t-butoxycarbonylaminocyclopropyl)pyrrolidine was added 350 mg of 5% palladium-on-carbon, and the mixture was shaken in a hydrogen stream (3.5 kg/cm2) for 1.5 hours. The catalyst was removed by filtration, and the solvent was evaporated under reduced pressure to give 213.0 mg (99.7%) of the title compound as a colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06391889B1
Source datasetuspto-grants-2002_05
ORD IDord-7941a4995ced40ed80a61dbc6b325ee3
Source noteuspto-grants-2002_05