HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15922606, compound → HCID 54160248, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15922606 | HCID 15922606 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54160248 | HCID 54160248 | 100.1% |
Reaction Steps
To 10 ml of an ethanol solution of 340.4 mg (0.94 mmol) of 1-benzyloxycarbonyl-3-(cis-2-t-butoxycarbonylaminocyclopropyl)pyrrolidine was added 350 mg of 5% palladium-on-carbon, and the mixture was shaken in a hydrogen stream (3.5 kg/cm2) for 1.5 hours. The catalyst was removed by filtration, and the solvent was evaporated under reduced pressure to give 213.0 mg (99.7%) of the title compound as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06391889B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-7941a4995ced40ed80a61dbc6b325ee3 |
| Source note | uspto-grants-2002_05 |