HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 3-(2-Propoxybenzamido)isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-Aminoisonicotinamide | HCID 10749239 | — |
| Reactant | 2-Propoxybenzoyl chloride | HCID 15921913 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-(2-Propoxybenzamido)isonicotinamide | HCID 22462376 | — |
Reaction Steps
In a similar manner to Example 68 a) reaction of 2-propoxybenzoyl chloride (0.99 g), 3-aminoisonicotinamide (0.69 g) and triethylamine (0.51 g) in acetonitrile (15 ml) afforded a crude product (1.45 g) which was recrystallized from methanol to afford 3-(2-propoxybenzamido)isonicotinamide, 0.73 g, m.p. 214-7° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06391885B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-0228b27a0cab4685bf96ff82d2af87c8 |
| Source note | uspto-grants-2002_05 |