HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86758080, compound → HCID 86758079, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86758080 | HCID 86758080 | — |
| Reactant | HCID 178418668 | HCID 178418668 | — |
| Solvent | Dichloromethane methanol acetic acid water | HCID 18914200 | — |
| Product | HCID 86758079 | HCID 86758079 | 91.3% |
Reaction Steps
The operation is carried out as in Example 1 Stages A, B and C but using 440 mg of ketone (obtained in Stage A of Example 1) and 342 mg of aminoguanidine hydrochloride. 380 mg of expected product is obtained after chromatography (eluent CH2Cl2/MeOH/H2O/AcOH 90/10/1/1) in the form of an E/Z mixture 85/15.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06391904B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-7b1f82550a5f4988bb99dce592fe6442 |
| Source note | uspto-grants-2002_05 |