HuagongsheHuagongshe Chemistry Print Report · For research reference only
Guaiacylacetone → HCID 86758081, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Guaiacylacetone | HCID 17262 | — |
| Reactant | 2-Hydrazino-delta-2-imidazoline hydrobromide | HCID 3085099 | — |
| Reactant | HCID 15857342 | HCID 15857342 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86758081 | HCID 86758081 | 0.8% |
Reaction Steps
The operation is carried out as in Example 1 Stages A, B and C but using 900 mg of 3-(4-hydroxy-3-methoxyphenyl)-2-propanone and 1.80 g of ethyl 4-bromo-2-[[(phenylmethoxy)carbonyl]amino]butanoate (Stage A) then, during Stage B, 1.47 g of 4,5-dihydro-1H-imidazol-2-yl-hydrazine hydrobromide. The saponificaton stage is carried out in the presence of soda in methanol. 20 mg of expected product is obtained in the form of an E/7 mixture 90/10
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06391904B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-3342d9d747044377846e379a2c301161 |
| Source note | uspto-grants-2002_05 |