(4-Aminophenoxy)benzene → HCID 22609760, compound

HRID 1936791Notes

Reaction equation

HRID 1936791 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]3[O:13][C:14]([CH3:17])=[N:15][N:16]=3)[CH:10]=2)[N:5]=[CH:4][N:3]=1.[O:18]([C:25]1[CH:31]=[CH:30][C:28]([NH2:29])=[CH:27][CH:26]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[ClH:1].[O:18]([C:25]1[CH:26]=[CH:27][C:28]([NH:29][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[C:9]([C:12]4[O:13][C:14]([CH3:17])=[N:15][N:16]=4)[CH:10]=3)[N:5]=[CH:4][N:3]=2)=[CH:30][CH:31]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 8764(4-Aminophenoxy)benzeneHCID 226097254-Chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazoline

Product 1

HCID 22609760HCID 22609760, compound

Procedure

4-Chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazoline was treated with 4-phenoxyaniline according to Procedure A to give the title compound as a yellow solid; δH [2H6]DMSO 11.78 (1H,bs), 9.45(1H,s), 8.95 (1H,s), 8.60(1H,dd), 8.10 (1H,d), 7.75 (2H,d) 7.45(2H,d), 7.10(5H,m), 2.68(3H,s); m/z (M+1+) 396.

Sources & evidence

ORD record
ord-8b7c358142b545c0aff34033afc270d0
Source dataset
uspto-grants-2002_05
Patent number
US06391874B1

Reaction notes

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