3-Chloro-4-[(2-fluorophenyl)methoxy]aniline → HCID 22609866, compound

HRID 1936795Notes

Reaction equation

HRID 1936795 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1[O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[F:17])[NH2:5].Cl[C:19]1[C:28]2[C:23](=[CH:24][CH:25]=[C:26]([C:29]3[O:30][C:31]([CH3:34])=[N:32][N:33]=3)[CH:27]=2)[N:22]=[CH:21][N:20]=1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([NH:5][C:19]2[C:28]3[C:23](=[CH:24][CH:25]=[C:26]([C:29]4[O:30][C:31]([CH3:34])=[N:32][N:33]=4)[CH:27]=3)[N:22]=[CH:21][N:20]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[F:17]

Participants

3

Reactant 2

HCID 219521053-Chloro-4-[(2-fluorophenyl)methoxy]anilineHCID 226097254-Chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazoline

Product 1

HCID 22609866HCID 22609866, compound

Procedure

The title compound was prepared according to Procedure A from 3-chloro4-(2-fluoro-benzyloxy)aniline and 4-chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)-quinazoline; δH [2H6]DMSO 11.64(1H,bs), 9.40(1H,s), 8.97(1H,s), 8.58(1H,d), 8.11(1H,d), 7.94(1H,d), 7.71(1H,dd), 7.63(1H,dd), 7.45(2H,m), 7.30(2H,m), 5.31 (2H,s), 2.68(3H,s); m/z (M+1+) 462.

Sources & evidence

ORD record
ord-bb4086a006a740d7a54ef10e1723705a
Source dataset
uspto-grants-2002_05
Patent number
US06391874B1

Reaction notes

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