4-(3-Fluoro-benzyloxy)-phenylamine → HCID 22609775, compound

HRID 1936799Notes

Reaction equation

HRID 1936799 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[CH2:5][O:6][C:7]1[CH:13]=[CH:12][C:10]([NH2:11])=[CH:9][CH:8]=1.[Cl:17][C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[C:25]([C:28]3[O:29][C:30]([CH3:33])=[N:31][N:32]=3)[CH:26]=2)[N:21]=[CH:20][N:19]=1>>[ClH:17].[F:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[CH2:5][O:6][C:7]1[CH:13]=[CH:12][C:10]([NH:11][C:20]2[N:19]=[CH:18][C:27]3[C:22](=[CH:23][CH:24]=[C:25]([C:28]4[O:29][C:30]([CH3:33])=[N:31][N:32]=4)[CH:26]=3)[N:21]=2)=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 167753144-(3-Fluoro-benzyloxy)-phenylamineHCID 226097254-Chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazoline

Product 1

HCID 22609775HCID 22609775, compound

Procedure

The title compound was prepared according to Procedure A from 4-(3-fluoro-benzyloxy)aniline and 4-chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)-quinazoline; δH [2H6]DMSO 11.71(1H,bs), 9.40(1H,s), 8.90(1H,s), 8.58(1H,d), 8.09(1H,d), 7.66(2H,d), 7.47(1H,m), 7.33(2H,m), 7.15(3H,m), 5.21(2H,s), 2.65(3H,s); m/z (M+1+) 428.

Sources & evidence

ORD record
ord-229753e9024d4fe1b398325a9cf4e5eb
Source dataset
uspto-grants-2002_05
Patent number
US06391874B1

Reaction notes

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