4-(4-Fluoro-benzyloxy)-phenylamine → HCID 22609766, compound

HRID 1936802Notes

Reaction equation

HRID 1936802 reaction equation
[F:1][C:2]1[CH:16]=[CH:15][C:5]([CH2:6][O:7][C:8]2[CH:14]=[CH:13][C:11]([NH2:12])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[Cl:17][C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[C:25]([C:28]3[O:29][C:30]([CH3:33])=[N:31][N:32]=3)[CH:26]=2)[N:21]=[CH:20][N:19]=1>>[ClH:17].[F:1][C:2]1[CH:16]=[CH:15][C:5]([CH2:6][O:7][C:8]2[CH:14]=[CH:13][C:11]([NH:12][C:18]3[C:27]4[C:22](=[CH:23][CH:24]=[C:25]([C:28]5[O:29][C:30]([CH3:33])=[N:31][N:32]=5)[CH:26]=4)[N:21]=[CH:20][N:19]=3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 64860214-(4-Fluoro-benzyloxy)-phenylamineHCID 226097254-Chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazoline

Product 1

HCID 22609766HCID 22609766, compound

Procedure

The title compound was prepared according to Procedure A from 4-(4-fluoro-benzyloxy)aniline and 4-chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)-quinazoline; δH [2H6]DMSO 11.68(1H,bs), 9.39(1H,s), 8.89(1H,s), 8.56(1H,d), 8.07(1H,d), 7.64(2H,d), 7.54(2H,m), 7.24(2H,dd), 7.14(2H,d), 5.14(2H,s), 2.65(3H,s); m/z (M+1+) 428.

Sources & evidence

ORD record
ord-25944949859f4889a375d7a0c1a38703
Source dataset
uspto-grants-2002_05
Patent number
US06391874B1

Reaction notes

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