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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1936816Generated: November 1, 2026

4-Benzyloxyaniline → (4-Benzyloxy-phenyl)-(6-(5-trifluoromethyl-1,3,4-oxadiazol-2-yl)-quinazolin-4-yl)-amine

https://huagongshe.com/reaction/1936816

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BenzyloxyanilineHCID 22860—
Reactant4-Chloro-6-(5-trifluoromethyl-1,3,4-oxadiazol-2-yl)quinazolineHCID 22609756—
Product(4-Benzyloxy-phenyl)-(6-(5-trifluoromethyl-1,3,4-oxadiazol-2-yl)-quinazolin-4-yl)-amineHCID 22609819—

Reaction Steps

The title compound was prepared according to Procedure A from 4-benzyloxyaniline and 4-chloro-6-(5-trifluoromethyl-1,3,4-oxadiazol-2-yl)-quinazoline; δH [2H6]DMSO 11.69(1H,bs), 9.53(1H,s), 8.91(1H,s), 8.65(1H,dd), 8.11(1H,d), 7.64(2H,d), 7.45(5H,m), 7.15(2H,d), 5.19(2H,s); m/z (M+1+) 464.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06391874B1
Source datasetuspto-grants-2002_05
ORD IDord-c2fa19550e744cf4ba0f92d22d50ba1f
Source noteuspto-grants-2002_05