HRID1936911

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5289077

Methyl (2S)-2-hydroxy-3-phenylpropanoate

C10H12O3

反应SMILES：Cc1sc(Cc2ccccc2)c(-c2ccc(-c3ccc(O)cc3)cc2)c1C

HCID22462573

未命名化合物

PRODUCTS

产物

反应SMILES：Cc1sc(Cc2ccccc2)c(-c2ccc(-c3ccc(O[C@H](Cc4ccccc4)C(=O)O)cc3)cc2)c1C

HCID10744488

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 4′-(2-benzyl-4,5-dimethyl-thiophen-3-yl)-biphenyl-4-ol, and (S)-(−)-3-phenyllactic acid methyl ester, in substantially the same manner, as described in Example 29, and was obtained as an off-white solid, mp 142-144° C.; MS m/e 517 (M−H)+;

WORKUP

后处理

customwas obtained as an off-white solid, mp 142-144° C.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-aee76b7ee979405b96145bafb1d3167a
来源数据集: uspto-grants-2002_05
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US06391897B2
来源说明: uspto-grants-2002_05

反应SMILES

[CH2:1]([C:8]1[S:9][C:10]([CH3:27])=[C:11]([CH3:26])[C:12]=1[C:13]1[CH:18]=[CH:17][C:16]([C:19]2[CH:24]=[CH:23][C:22]([OH:25])=[CH:21][CH:20]=2)=[CH:15][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[O:29][C:30](=[O:40])[C@H:31]([CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)O>>[CH2:1]([C:8]1[S:9][C:10]([CH3:27])=[C:11]([CH3:26])[C:12]=1[C:13]1[CH:18]=[CH:17][C:16]([C:19]2[CH:20]=[CH:21][C:22]([O:25][C@H:31]([CH2:33][C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)[C:30]([OH:40])=[O:29])=[CH:23][CH:24]=2)=[CH:15][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1