Lawesson's reagent → HCID 22462450, compound

HRID 1936983Notes

Reaction equation

HRID 1936983 reaction equation
[CH3:1][C:2]1[C:11]([N+:12]([O-:14])=[O:13])=[CH:10][C:9]2[NH:8][C:7](=O)[CH:6]3[CH2:16][CH2:17][CH2:18][CH:5]3[C:4]=2[CH:3]=1.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:28])=CC=1>>[CH3:1][C:2]1[C:11]([N+:12]([O-:14])=[O:13])=[CH:10][C:9]2[NH:8][C:7](=[S:28])[CH:6]3[CH2:16][CH2:17][CH2:18][CH:5]3[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 87949Lawesson's reagentHCID 22462507HCID 22462507, compound

Product 1

HCID 22462450HCID 22462450, compoundYield 75%

Procedure

As described for Example 4, 8-methyl-7-nitro-1,2,3,3a,5,9b-hexahydrocyclopenta[c]quinolin-4-one (60 mg, 0.24 mmol) is reacted with Lawesson's reagent (105 mg, 0.26 mmol) to form 47 mg (75%) of product.

Sources & evidence

ORD record
ord-87c873c4d3e14e909b2cd811f50aad55
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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