Ammonia → HCID 22462429, compound

HRID 1936984Notes

Reaction equation

HRID 1936984 reaction equation
C[C:2]1[C:11]([N+:12]([O-:14])=[O:13])=[CH:10][C:9]2[NH:8][C:7](=S)[CH:6]3[CH2:16][CH2:17][CH2:18][CH:5]3[C:4]=2[CH:3]=1.[NH3:19]>>[NH2:19][C:7]1[CH:6]2[CH2:16][CH2:17][CH2:18][CH:5]2[C:4]2[CH:3]=[CH:2][C:11]([N+:12]([O-:14])=[O:13])=[CH:10][C:9]=2[N:8]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 22462450HCID 22462450, compound

Product 1

HCID 22462429HCID 22462429, compoundYield 77%

Procedure

As described for Example 4, 8-methyl-7-nitro-1,2,3,3a,5,9b-hexahydrocyclopenta[c]quinoline-4-thione (42 mg, 0.16 mmol) is reacted with 7N methanolic ammonia solution (10 ml) to form 30 mg (77%) of product.

Sources & evidence

ORD record
ord-81696a553ffa4714b5c5af15c60c7b7f
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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