Ammonia → HCID 22462467, compound

HRID 1936986Notes

Reaction equation

HRID 1936986 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][C:11]2[NH:10][C:9](=S)[CH:8]3[CH2:15][CH2:16][CH2:17][CH:7]3[C:6]=2[CH:5]=1)([O-:3])=[O:2].[NH3:18]>>[NH2:18][C:9]1[CH:8]2[CH2:15][CH2:16][CH2:17][CH:7]2[C:6]2[CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:13]=[CH:12][C:11]=2[N:10]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 22462472HCID 22462472, compound

Product 1

HCID 22462467HCID 22462467, compoundYield 76%

Procedure

As described for Example 4, 8-nitro-1,2,3,3a,5,9b-hexahydrocyclopenta[c]quinoline-4-thione (100 mg, 0.40 mmol) is reacted with 7N methanolic ammonia solution (15 ml) to form 70 mg (76%) of product.

Sources & evidence

ORD record
ord-03acb2bd3d794280b2bc5ecc8bd5069e
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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