Lawesson's reagent → HCID 22462441, compound

HRID 1936990Notes

Reaction equation

HRID 1936990 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:7]3[CH2:16][CH2:15][CH2:14][CH:8]3[C:9](=O)[NH:10][C:11]=2[CH:12]=1.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:26])=CC=1>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:7]3[CH2:16][CH2:15][CH2:14][CH:8]3[C:9](=[S:26])[NH:10][C:11]=2[CH:12]=1

Participants

3

Reactant 2

HCID 87949Lawesson's reagentHCID 22462448HCID 22462448, compound

Product 1

HCID 22462441HCID 22462441, compoundYield 78%

Procedure

Analogously to Example 4, 7-methoxy-1,2,3,3a,5,9b-hexahydrocyclopenta[c]quinolin-4-one (180 mg, 0.83 mmol) is reacted with Lawesson's reagent (370 mg, 0.91 mmol) to form 150 mg (78%) of product.

Sources & evidence

ORD record
ord-6ae6791c891b431bb77e712c9531a3c7
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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