Ammonia → HCID 22462482, compound

HRID 1936991Notes

Reaction equation

HRID 1936991 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:7]3[CH2:16][CH2:15][CH2:14][CH:8]3[C:9](=S)[NH:10][C:11]=2[CH:12]=1.[NH3:17]>>[NH2:17][C:9]1[CH:8]2[CH2:14][CH2:15][CH2:16][CH:7]2[C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:12][C:11]=2[N:10]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 22462441HCID 22462441, compound

Product 1

HCID 22462482HCID 22462482, compoundYield 79%

Procedure

Analogously to Example 4, 7-methoxy-1,2,3,3a,5,9b-hexahydrocyclopenta[c]quinoline-4-thione (150 mg, 0.64 mmol) in 7N methanolic ammonia solution (25 ml) is reacted to form 110 mg (79%) of product.

Sources & evidence

ORD record
ord-797764594f5e4808b2535b36e8896e87
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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