Ammonia → HCID 22462463, compound

HRID 1936995Notes

Reaction equation

HRID 1936995 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[CH:6]3[CH2:15][CH2:14][CH2:13][CH:7]3[C:8](=S)[NH:9][C:10]=2[CH:11]=1.[NH3:16]>>[NH2:16][C:8]1[CH:7]2[CH2:13][CH2:14][CH2:15][CH:6]2[C:5]2[CH:4]=[CH:3][C:2]([CH3:1])=[CH:11][C:10]=2[N:9]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 86758085HCID 86758085, compound

Product 1

HCID 22462463HCID 22462463, compoundYield 99%

Procedure

In a way that is similar to Example 4, 7-methyl-1,2,3,3a,5,9b-hexahy drocyclopenta[c]quinoline-4-thione (230 mg, 1.05 mmol) in 7N methanolic ammonia solution (25 ml) is reacted to form 210 mg (99%) of product.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-794d5a691b424d9dae78a333f89cf11c
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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