Lawesson's reagent → HCID 22462496, compound

HRID 1937018Notes

Reaction equation

HRID 1937018 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[CH:8][C:9]2[CH:10]3[CH2:19][CH2:18][CH2:17][CH:11]3[C:12](=O)[NH:13][C:14]=2[CH:15]=1.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:29])=CC=1>>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[CH:8][C:9]2[CH:10]3[CH2:19][CH2:18][CH2:17][CH:11]3[C:12](=[S:29])[NH:13][C:14]=2[CH:15]=1

Participants

3

Reactant 2

HCID 87949Lawesson's reagentHCID 15429323HCID 15429323, compound

Product 1

HCID 22462496HCID 22462496, compoundYield 98%

Procedure

Analogously to Example 4, 7-(2-furanyl)-1,2,3,3a,5,9b-hexahydrocyclopenta[c]quinolin-4-one (100 mg, 0.39 mmol) is reacted with Lawesson's reagent (404 mg, 1.0 mmol) to form 103 mg (98%) of product.

Sources & evidence

ORD record
ord-740a5baf9f5d4c1a876829a7cf64a85d
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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