Ammonia → HCID 22462466, compound

HRID 1937023Notes

Reaction equation

HRID 1937023 reaction equation
[N:1]1([C:7]2[CH:8]=[CH:9][C:10]3[CH:11]4[CH2:20][CH2:19][CH2:18][CH:12]4[C:13](=S)[NH:14][C:15]=3[CH:16]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[NH3:21]>>[NH2:21][C:13]1[CH:12]2[CH2:18][CH2:19][CH2:20][CH:11]2[C:10]2[CH:9]=[CH:8][C:7]([N:1]3[CH2:6][CH2:5][O:4][CH2:3][CH2:2]3)=[CH:16][C:15]=2[N:14]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 22462430HCID 22462430, compound

Product 1

HCID 22462466HCID 22462466, compoundYield 53%

Procedure

Analogously to Example 4, 7-(4-morpholinyl)-1,2,3,3a,5,9b-hexahydrocyclopenta[c]quinoline-4-thione (80 mg, 0.28 mmol) in 7N methanolic ammonia solution (15 ml) is reacted to form 40 mg (53%) of product.

Sources & evidence

ORD record
ord-cc09813e9108419d846131fb98c9a1e9
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

Loading…