Magnesium → HCID 18516355, compound

Participants

Reaction Steps

A solution of 7-(methoxycarbonylethenyl)-1,2,3,5-tetrahydrocyclopenta[c]quinolin-4-one (550 mg, 2.0 mmol) in methanol-THF 3:1 (130 ml) is mixed with magnesium (972 mg, 40.0 mmol) and stirred for 24 hours at room temperature. The reaction mixture is filtered on spun glass, the filter residue is washed with dichloromethane-methanol, and the combined filtrates are concentrated by evaporation in a vacuum. Purification of the residue on silica gel yields 120 mg (22%) of product.

Provenance & Evidence