Ammonia → HCID 69849085, compound

HRID 1937027Notes

Reaction equation

HRID 1937027 reaction equation
[CH3:1][O:2][C:3]([CH2:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]2[CH:11]3[CH2:20][CH2:19][CH2:18][CH:12]3[C:13](=S)[NH:14][C:15]=2[CH:16]=1)=[O:4].[NH3:21]>>[NH2:21][C:13]1[CH:12]2[CH2:18][CH2:19][CH2:20][CH:11]2[C:10]2[CH:9]=[CH:8][C:7]([CH2:6][CH2:5][C:3]([O:2][CH3:1])=[O:4])=[CH:16][C:15]=2[N:14]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 86758086HCID 86758086, compound

Product 1

HCID 69849085HCID 69849085, compoundYield 28%

Procedure

Analogously to Example 4, 7-(methoxycarbonylethyl)-1,2,3,3a,5,9b-hexahydrocyclopenta[c]quinoline-4-thione (150 mg, 0.52 mmol) in 7N methanolic ammonia solution (20 ml) is reacted to form 40 mg (28%) of product.

Sources & evidence

ORD record
ord-b565c9199d954108bb35a07a550e92f8
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

Loading…