Potassium Carbonate → HCID 10130413, compound

Participants

Reaction Steps

50 mmol of methyl 2-chlorofuran-4-carboxylate were heated with 52 mmol of phenylboronic acid, 50 mmol of potassium carbonate, 25 mmol of lithium chloride and 0.25 mmol of trans-di-μ-acetato-bis[2-[bis(1,1-dimethylethyl)phosphino]-2-methylpropyl-C,P]dipalladium (1 mol %) in 150 ml of dibutylether at 80° C. for 8 hours. Aqueous work-up, filtration through a short silica gel column and distilling off the solvent leaves methyl 2-phenylfuran-4-carboxylate as a colorless residue. Yield: 85%.

Provenance & Evidence