反应详情

In the same manner as that described in Example 7(iv) above 7.00 g (18.7 mmol) of (2R,3 R)-2-(2,5-difluorophenyl)-1,3-bis(methanesulfonyl)-2-butanol [prepared as described in Step 8(iii) above] were reacted with 1H-1,2,4-triazole and the reaction product was purified by chromatography on a silica gel (100 g) column using a 1:1 to 3:2 mixture of ethyl acetate and hexane as the eluant to afford 2.65 g (yield 56%) of the title compound as an oil.

1. customthe reaction product was purified by chromatography on a silica gel (100 g) column
2. additionto 3:2 mixture of ethyl acetate and hexane as the eluant