HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 22462783, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 6-Benzyloxy-2-dimethylaminobenzo[b]thiophene | HCID 10612994 | — |
| Reactant | 84449-68-3 | HCID 22462683 | — |
| Product | HCID 22462783 | HCID 22462783 | 38% |
Reaction Steps
By essentially following the proceedure described in Example 16, Part A, the title compound was prepared as an oil starting from 6-benzyloxy-2-dimethylaminobenzo[b]thiophene and 4-[2-(1-pyrrolidinyl)ethoxy]benzoyl chloride hydrochloride in 38% yield following MPLC (SiO2; 15% then 20% then 30% THF with 5% TEA in hexanes).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06391901B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-91887b3e704b464294558b62f808af3c |
| Source note | uspto-grants-2002_05 |