HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 1-(N,N-dimethylcarbamoyl)-3-methoxycarbonyladamantane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Chloride | HCID 312 | — |
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 5-Hydroxy-1,3-adamantanedicarboxylic acid | HCID 12010644 | — |
| Reactant | 1,3-Dicarboxy-5,7-adamantanediol | HCID 12070463 | — |
| Reactant | 1-(N,N-dimethylcarbamoyl)-3-adamantanol | HCID 12070471 | — |
| Reactant | 1,3-Di(hydrazinocarbonyl)-5,7-adamantanediol | HCID 17780684 | — |
| Product | 1-(N,N-dimethylcarbamoyl)-3-methoxycarbonyladamantane | HCID 18410477 | — |
Reaction Steps
For example, reaction of 1,3-dicarboxy-5-adamantanol with ammonia provides 1,3-dicarbamoyl-5-admatanol. Reaction of 1,3-dicarboxy-5,7-adamantanediol with hydrazine forms 1, 3-di(hydrazinocarbonyl)-5,7-adamantanediol, etc. 1-(N, N-dimethylcarbamoyl)-3-adamantanol can be obtained by acting thyonyl chloride on 1-carboxy-3-adamantanol followed by reacting the resultant compound with dimethylamine. Similarly, 1-(N,N-dimethylcarbamoyl)-3-methoxycarbonyladamantane can be formed from 1-carboxy-3-methoxycarbonyladamatane,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06392104B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-fec9ebdf20f14026916ff8913e9aa418 |
| Source note | uspto-grants-2002_05 |