Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | HCID 3522593 | HCID 3522593 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 12070472 | HCID 12070472 | 95% |
Reaction Steps
In an atmosphere of nitrogen, 10 mmole of 1-nitro-3-adamantanol obtained by the method of Example 4 and 12 mmole of triethylamine were dissolved in 10 ml of DMF. To the mixture, 11 mmole of acetyl chloride was added dropwise over 30 minutes at 40° C. The mixture was stirred for another 3 hours at 40° C. As a result, the conversion of 1-nitro-3-adamantanol was 99%, and 1-acetyloxy-3-nitroadamantane (yield 95%) was formed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06392104B1 |
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| Source dataset | uspto-grants-2002_05 |
|---|
| ORD ID | ord-a47dc77dfce54526afc524759c61e515 |
|---|
| Source note | uspto-grants-2002_05 |
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