Aniline → HCID 22460824, compound

HRID 1937393Notes

Reaction equation

HRID 1937393 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:9]1[C:10]2[CH:18]=[CH:17][N:16]=[CH:15][C:11]=2[N:12]=[CH:13][N:14]=1>>[C:2]1([NH:1][C:13]2[N:14]=[CH:9][C:10]3[CH:18]=[CH:17][N:16]=[CH:15][C:11]=3[N:12]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 122716344-Chloropyrido(3,4-d)pyrimidine

Product 1

HCID 22460824HCID 22460824, compoundYield 22%

Procedure

Using a procedure analogous to that described in Example 5, this product was prepared in 22% yield from aniline (1.8 eq.) and 4-chloropyrido[3,4-d]pyrimidine (1 eq.). MP 161° C.; LC-MS: 223 (MH+).

Sources & evidence

ORD record
ord-e248ff6eec6248d6bdfc61fed2b73bed
Source dataset
uspto-grants-2002_05
Patent number
US06395733B1

Reaction notes

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