Methyl iodide → HCID 22460891, compound

HRID 1937397Notes

Reaction equation

HRID 1937397 reaction equation
[Cl:1][C:2]1[C:3]2[CH:10]=[CH:9][NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[CH3:11]I.[NH2:13][C:14]1[CH:15]=[C:16]([C:20]#[CH:21])[CH:17]=[CH:18][CH:19]=1>>[ClH:1].[C:20]([C:16]1[CH:15]=[C:14]([NH:13][C:2]2[C:3]3[CH:10]=[CH:9][N:8]([CH3:11])[C:4]=3[N:5]=[CH:6][N:7]=2)[CH:19]=[CH:18][CH:17]=1)#[CH:21]

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 104682Benzenamine, 3-ethynyl-HCID 53566827H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-

Product 1

HCID 22460891HCID 22460891, compound

Procedure

Following the procedure described in Example 1, the title compound was prepared from 4-chloro-7H-pyrrolo[2,3-d]pyrimidine and methyl iodide, and m-aminophenyl acetylene (75%). TS-MS: 249 (MH+); anal. RP18-HPLC RT: min.

Workup

  1. customRP18-HPLC RT

Sources & evidence

ORD record
ord-a914e461e875416d8becc15e046ccb88
Source dataset
uspto-grants-2002_05
Patent number
US06395733B1

Reaction notes

Loading…