HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 22557990, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine | HCID 12019237 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 22557990 | HCID 22557990 | — |
Reaction Steps
To a solution of 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (881 mg) in chloroform (10 mL) was added potassium phthalimide (556 mg). The mixture was stirred at room temperature overnight and water was added. After separating the organic layer, the aqueous layer was extracted with chloroform. Organic layers were combined, dried over anhydrous magnesium sulfate and evaporated to give the title compound as white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06395753B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-790d03ea1e9646f899f2956324e353fc |
| Source note | uspto-grants-2002_05 |