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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1937676Generated: November 1, 2026

Ethyl 2-chloroisonicotinate → Ethyl 2-(4-chloro-3,5-dimethoxyphenyl)isonicotinate

https://huagongshe.com/reaction/1937676

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-chloroisonicotinateHCID 2762942—
Reactant(4-Chloro-3,5-dimethoxyphenyl)boronic acidHCID 22485557—
ProductEthyl 2-(4-chloro-3,5-dimethoxyphenyl)isonicotinateHCID 22557799—

Reaction Steps

4-Chloro-3,5-dimethoxyphenylboronic acid (7.45 g) and ethyl 2-chloroisonicotinate (6.39 g) were condensend in the same manner as described in Preparation Example 1 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06395753B1
Source datasetuspto-grants-2002_05
ORD IDord-e2c5e526344345818119beaa7c91934f
Source noteuspto-grants-2002_05