Dimethyl Sulfoxide → N-[5-(4-Amino-3-bromo-phenyl)-4-methyl-thiazol-2-yl]acetamide

HRID 193776Notes

Reaction equation

HRID 193776 reaction equation
[CH3:26][S:27]([CH3:28])=[O:29].[NH2:9][c:10]1[cH:11][cH:12][c:13](-[c:16]2[c:17]([CH3:25])[n:18][c:19]([NH:21][C:22]([CH3:23])=[O:24])[s:20]2)[cH:14][cH:15]1.[O:1]=[C:2]1[N:3]([Br:8])[C:4](=[O:5])[CH2:6][CH2:7]1.[OH2:30]>>[Br:8][c:15]1[c:10]([NH2:9])[cH:11][cH:12][c:13](-[c:16]2[c:17]([CH3:25])[n:18][c:19]([NH:21][C:22]([CH3:23])=[O:24])[s:20]2)[cH:14]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 67184N-bromobutanimideHCID 85861718N-[5-(4-amino-phenyl)-4-methyl-thiazol-2-yl]-acetamide

Product 1

HCID 85861724N-[5-(4-Amino-3-bromo-phenyl)-4-methyl-thiazol-2-yl]acetamide

Sources & evidence

ORD record
ord-ee1752da44714a62923354c86349a464
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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