Trimethyl orthoformate → HCID 11356486, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred mixture of 17.7 g methyl-trans-3-methoxyacrylate and 32.3 g trimethyl ortho formate was added 0.4 g FeCl3. The mixture was heated to 40° C. for 24 hours, whereby 0.2 g FeCl3 were added every 6 hours. After cooling to room temperature, 5.00 g anhydrous sodium carbonate were added and the reaction mixture was stirred for 2 hours. Filtering, washing the filter-cake washed with trimethyl ortho formate and fractional distillation gave 13.5 g colorless liquid (80% of theoretical based on converted methyl-trans-3-methoxyacrylate) of boiling point 100° C./4 mm Hg. GC-analysis of the liquid revealed an assay of >99% (FID-detection).

Provenance & Evidence