HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-(-)-Glycidyl-4-nitrobenzenesulfonate → (R)-2-Cyano-5-(3-carbethoxypropyl)phenyl Glycidyl Ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-(-)-Glycidyl-4-nitrobenzenesulfonate | HCID 14292098 | — |
| Reactant | Ethyl 4-(4-cyano-3-hydroxyphenyl)butanoate | HCID 22461711 | — |
| Product | (R)-2-Cyano-5-(3-carbethoxypropyl)phenyl Glycidyl Ether | HCID 88171297 | 89% |
Reaction Steps
Using the method of example 30(b), vide supra, ethyl 4-(4-cyano-3-hydroxyphenyl)butanoate (1.4 g, 6 mmol) and (R)-glycidyl nosylate (1.48 g, 5.71 mmol) were used to prepare 1.47 g (88%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06395919B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-afd2c80f22304125b502a4258019c311 |
| Source note | uspto-grants-2002_05 |