HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(4-cyano-3-hydroxyphenyl)propanoate → ethyl (R)-4-cyano-3-(oxiranylmethoxy)benzenepropionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(4-cyano-3-hydroxyphenyl)propanoate | HCID 9834402 | — |
| Reactant | (R)-(-)-Glycidyl-4-nitrobenzenesulfonate | HCID 14292098 | — |
| Product | ethyl (R)-4-cyano-3-(oxiranylmethoxy)benzenepropionate | HCID 58700132 | 86% |
Reaction Steps
Using the method of example 30(b), supra, ethyl 3-(4-cyano-3-hydroxyphenyl)propionate (1.32 g, 6 mmol) and (R)-glycidyl nosylate (1.48 g, 5.71 mmol) were used to prepare 1.35 g (86%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06395919B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-ade924d95d8d4d48ae019e668911e151 |
| Source note | uspto-grants-2002_05 |