HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-(-)-Glycidyl-4-nitrobenzenesulfonate → (R)-2-cyano-4-(3-carbethoxypropyl)phenyl Glycidyl Ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-(-)-Glycidyl-4-nitrobenzenesulfonate | HCID 14292098 | — |
| Reactant | Ethyl 4-(3-cyano-4-hydroxyphenyl)butanoate | HCID 22461719 | — |
| Product | (R)-2-cyano-4-(3-carbethoxypropyl)phenyl Glycidyl Ether | HCID 88171393 | 66.3% |
Reaction Steps
Using the method of example 30(b), supra, ethyl 4-(3-cyano-4-hydroxyphenyl)butanoate (0.93 g, 4 mmol) and (R)-glycidyl nosylate (1.00 g, 3.86 mmol) were used to prepare 0.74 g (66%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06395919B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-10cd4df174dd41129bd8c6dee2c5141a |
| Source note | uspto-grants-2002_05 |