3-Mercaptopyridine → HCID 23509041, compound

HRID 1937803Notes

Reaction equation

Br[C:2]1[N:7]([CH2:8][O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:6](=[O:16])[NH:5][C:4](=[O:17])[C:3]=1[CH2:18][CH3:19].[N:20]1[CH:25]=[CH:24][CH:23]=[C:22]([SH:26])[CH:21]=1>>[CH2:18]([C:3]1[C:4](=[O:17])[NH:5][C:6](=[O:16])[N:7]([CH2:8][O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:2]=1[S:26][C:22]1[CH:21]=[N:20][CH:25]=[CH:24][CH:23]=1)[CH3:19]

Participants

Reactant 2

HCID 276913-Mercaptopyridine

HCID 23509038HCID 23509038, compound

Product 1

HCID 23509041HCID 23509041, compound

Procedure

Likewise, 6-bromo-5-ethyl-1-(phenoxymethyl)-uracil and 3-pyridinethiol can be reacted according to the present method in order to yield a 5-ethyl-1-(phenoxymethyl)-6-(3-pyridylsulfanyl)-uracil.

Sources & evidence

ORD record: ord-b110e927adb1466092ddaf8dbc61f531
Source dataset: uspto-grants-2002_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06395939B1

Reaction notes

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