HuagongsheHuagongshe Chemistry Print Report · For research reference only
10,11-Dihydro-10-(4-nitrobenzoyl)dibenz[b,f][1,4]thiazepine → 10,11-Dihydro-10-(4-aminobenzoyl)dibenz[b,f][1,4]thiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 10,11-Dihydro-10-(4-nitrobenzoyl)dibenz[b,f][1,4]thiazepine | HCID 54570072 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 10,11-Dihydro-10-(4-aminobenzoyl)dibenz[b,f][1,4]thiazepine | HCID 54230002 | 89.2% |
Reaction Steps
A mixture of 2.2 g of 10,11-dihydro-10-(4-nitrobenzoyl)dibenz[b,f][1,4]thiazepine in 150 ml of methanol is shaken in a Parr hydrogenator under 50 pounds per square inch of hydrogen for 72 hours. The mixture is filtered through diatomaceous earth and the filtrate evaporated in vacuo. The residue is recrystallized from chloroform-hexane to give 1.8 g of crystals, m.p. 52°-55° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05693635 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-862e3b2ce9a64f5ca8110938894028a9 |
| Source note | uspto-grants-1997_12 |