2,4-Dichlorobenzoyl chloride → N-[4-[(6,11-Dihydro-5H-dibenz[b,e]azepin-5-yl)carbonyl]phenyl]2,4-dichlorobenzamide

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Reaction Steps

As described for Example 9, 0.111 g (1.1 mmol) of 5-(4-aminobenzoyl)-6,11-dihydro-5H-dibenz-[b,e]azepine in 8 ml of dichloromethane is reacted with 0.230 g of (1.1 mmol) of 2,4-dichlorobenzoyl chloride. The product is recrystallized from hexane-dichloromethane to give 0.24 g of crystals, m.p. 212°-215° C. Anal. Calc'd for C18H20Cl2 N2O2H2O: C,66.5; H,4.4; N,5.5. Found: C,66.8; H,4.0; N,5.5.

Provenance & Evidence