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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1938344Generated: October 26, 2026

3-Nitro-7-(5-ethyl-2-pyridylmethoxy)quinoline → 3-Amino-7-(5-ethyl-2-pyridylmethoxy)quinoline

https://huagongshe.com/reaction/1938344

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Nitro-7-(5-ethyl-2-pyridylmethoxy)quinolineHCID 21469290—
CatalystPlatinum oxide (PtO)HCID 82844—
SolventEthanolHCID 702—
Product3-Amino-7-(5-ethyl-2-pyridylmethoxy)quinolineHCID 21469277—

Reaction Steps

In ethanol (20 mL) was suspended 3-nitro-7-(5-ethyl-2-pyridylmethoxy)quinoline (700 mg, 2.26 mmol.), and to the suspension was added platinum oxide (80 mg). Then, catalytic reduction was performed for 3 hours. After the completion of reaction was confirmed, the reaction mixture was filtered over Celite®, and the filtrate was placed under reduced pressure to give the desired compound as residual oil in a quantitative yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05693651
Source datasetuspto-grants-1997_12
ORD IDord-6cdf47ffa16846fcb5a9aa3de90c89dd
Source noteuspto-grants-1997_12