HCID 54122524, compound → HCID 53921407, compound

Participants

Reaction Steps

The above 3-hydroxymethyl-7-(methylphenylamino)methylquinoline (306 mg, 1.10 mmol.) was dissolved in dry chloroform (8 mL). To this was added manganese dioxide (0.95 g), and the mixture was stirred overnight at room temperature. The reaction mixture was filtered over Celite®, and the residue was washed with chloroform. The chloroform washings were combined with the filtrate. The solvent was distilled off under reduced pressure, to leave the desired compound as brown oil (222 mg, yield: 73%).

Provenance & Evidence