HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 21469382, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | HCID 21469363 | HCID 21469363 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21469382 | HCID 21469382 | — |
Reaction Steps
A solution of 3.6 g of 3-[1-(4-(5-methoxycarbonylindol-3-yl)butyl)-4-piperidyl]indole in 40 ml of THF is added dropwise to a suspension of 0.6 g of lithium aluminum hydride in 20 ml of THF with stirring. The mixture is then stirred for a further hour at 25°, 20 ml of dilute sodium hydroxide solution are added, the mixture is filtered and the filtrate is worked up in a conventional manner. 3-[1-(4-(5-hydroxymethylindol-3-yl)butyl)-4-piperidyl]indole is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05693655 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-f3112b9a9b2e47f1a17f1e071647abae |
| Source note | uspto-grants-1997_12 |