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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1938364Generated: November 4, 2026

Sodium Hydroxide → HCID 21469382, compound

https://huagongshe.com/reaction/1938364

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantAluminium lithium hydrideHCID 21226445—
ReactantHCID 21469363HCID 21469363—
SolventTetrahydrofuranHCID 8028—
ProductHCID 21469382HCID 21469382—

Reaction Steps

A solution of 3.6 g of 3-[1-(4-(5-methoxycarbonylindol-3-yl)butyl)-4-piperidyl]indole in 40 ml of THF is added dropwise to a suspension of 0.6 g of lithium aluminum hydride in 20 ml of THF with stirring. The mixture is then stirred for a further hour at 25°, 20 ml of dilute sodium hydroxide solution are added, the mixture is filtered and the filtrate is worked up in a conventional manner. 3-[1-(4-(5-hydroxymethylindol-3-yl)butyl)-4-piperidyl]indole is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05693655
Source datasetuspto-grants-1997_12
ORD IDord-f3112b9a9b2e47f1a17f1e071647abae
Source noteuspto-grants-1997_12