tert-butyl N-[(3-sulfanyl-2-pyridinyl)methyl]carbamate → Benzhydryl 7-[[2-(2-amino-5-chloro-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[2-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]-3-pyridinyl]sulfanyl]-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

HRID 193849Notes

Reaction equation

HRID 193849 reaction equation
[NH2:1][c:2]1[s:3][c:4]([Cl:47])[c:5]([C:7]([C:8](=[O:9])[NH:10][CH:11]2[CH:12]3[CH2:13][CH2:14][C:15]([O:36][S:37]([C:38]([F:39])([F:40])[F:41])(=[O:42])=[O:43])=[C:16]([C:20](=[O:21])[O:22][CH:23]([c:24]4[cH:25][cH:26][cH:27][cH:28][cH:29]4)[c:30]4[cH:31][cH:32][cH:33][cH:34][cH:35]4)[N:17]3[C:18]2=[O:19])=[N:44][O:45][CH3:46])[n:6]1.[SH:48][c:49]1[c:50]([CH2:55][NH:56][C:57]([O:58][C:59]([CH3:60])([CH3:61])[CH3:62])=[O:63])[n:51][cH:52][cH:53][cH:54]1>>[NH2:1][c:2]1[s:3][c:4]([Cl:47])[c:5]([C:7]([C:8](=[O:9])[NH:10][CH:11]2[CH:12]3[CH2:13][CH2:14][C:15]([S:48][c:49]4[c:50]([CH2:55][NH:56][C:57]([O:58][C:59]([CH3:60])([CH3:61])[CH3:62])=[O:63])[n:51][cH:52][cH:53][cH:54]4)=[C:16]([C:20](=[O:21])[O:22][CH:23]([c:24]4[cH:25][cH:26][cH:27][cH:28][cH:29]4)[c:30]4[cH:31][cH:32][cH:33][cH:34][cH:35]4)[N:17]3[C:18]2=[O:19])=[N:44][O:45][CH3:46])[n:6]1

Participants

3

Reactant 2

HCID 86646729tert-butyl N-[(3-sulfanyl-2-pyridinyl)methyl]carbamateHCID 151630783Benzhydryl 7-[[2-(2-amino-5-chloro-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(trifluoromethylsulfonyloxy)-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Product 1

HCID 173088795Benzhydryl 7-[[2-(2-amino-5-chloro-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[2-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]-3-pyridinyl]sulfanyl]-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Sources & evidence

ORD record
ord-fa199cd75dd34133bfeb7655a749275f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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