HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-((1,3-Benzodioxol-5-ylmethyl)amino)-2,6-dichloro quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | 2,4,6-Trichloroquinazoline | HCID 10421510 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 4-((1,3-Benzodioxol-5-ylmethyl)amino)-2,6-dichloro quinazoline | HCID 22339865 | 96.9% |
Reaction Steps
A mixture comprising 3.6 g of 2,4,6-trichloroquinazoline, 2.4 g of piperonylamine, 1.6 g of triethylamine and 50 ml of isopropyl alcohol was heated under reflux for 1.5 hours and hot-filtered to give 5.2 g of the title compound as a filter cake.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05693652 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-ffa5856d1a834ed8afe7476546c0f5b6 |
| Source note | uspto-grants-1997_12 |