HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 178509652, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | HCID 21468924 | HCID 21468924 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178509652 | HCID 178509652 | 84.6% |
Reaction Steps
2-Chloromethyl-5-2-cyanophenyl)-1H-benzimidazole (2.28 mmoles, 0.54 g--see Example 35) and pyrrolidine (5.26 mole, 0.375 g.) were dissolved in THF and stirred at room temperature. The solvents were removed in vacuo. The residue was dissolved in ethyl acetate, washed with water, and concentrated to yield 0.583 g of 5-(2-Cyanophenyl)-2-(1-pyrrolidinomethyl)-1H-benzimidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05693633 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-62eef389a7e3468a8a473efc4945648b |
| Source note | uspto-grants-1997_12 |