HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → N-(4-benzoylphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Aminobenzophenone | HCID 14346 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(4-benzoylphenyl)acetamide | HCID 228532 | — |
Reaction Steps
Combine 4-aminobenzophenone (500 g, 2.54 mol) and triethylamine (307 g,3.03 mol) in dichloromethane (2.54 L). Add acetic anhydride (313.9 g, 3.07 mol). After 18 hours, add methanol (100 mL) and evaporate in vacuo to give a residue. Combine the residue and water (8 L) and stir to give a solid. Collect the solid by filtration, rinse repeatedly with water, and dry to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05693674 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-f6942d4b98e241ecb82e12785f19b6ae |
| Source note | uspto-grants-1997_12 |