HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Difluoroaniline → N-(2,4-Difluoro-phenyl)-2-(3-dodecyl-isoxazol-5-yl)-2-phenyl-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Difluoroaniline | HCID 9709 | — |
| Reactant | 5-Dodecyl-alpha-phenyl-3-isoxazole acetic acid | HCID 10523277 | — |
| Reactant | 3-Dodecyl-alpha-phenyl-5-isoxazole acetic acid | HCID 10833056 | — |
| Product | N-(2,4-Difluoro-phenyl)-2-(3-dodecyl-isoxazol-5-yl)-2-phenyl-acetamide | HCID 18955387 | — |
Reaction Steps
In a manner similar to Example 128, a mixture of 3-dodecyl-α-phenyl-5-isoxazole acetic acid and 5-dodecyl-α-phenyl-3-isoxazole acetic acid was condensed with 2,4-difluoroaniline to give, after chromatography, pure title compound; mp 68°-70° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05693657 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-4a7c39cdd74044f2bd9ff998d4c8d192 |
| Source note | uspto-grants-1997_12 |