Hydrazine → Tridecanoic acid hydrazide

HRID 1938741Notes

Reaction equation

HRID 1938741 reaction equation
[C:1]([O:15]C)(=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[NH2:17][NH2:18]>C(O)C>[C:1]([NH:17][NH2:18])(=[O:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 15608Methyl tridecanoate

Product 1

HCID 10823265Tridecanoic acid hydrazide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of tridecanoic acid, methyl ester (24.63 g, 0.1078 mol), and anhydrous hydrazine (3.40 mL, 0.108 mol) in absolute ethanol (150 mL) was stirred at room temperature for 24 hours, then refluxed 2 days. The solution was allowed to cool, and the solid that crystallized was filtered off, washed, and dried in vacuo; yield 18.6 g (75%); mp 101°-104° C.

Workup

  1. temperaturerefluxed 2 days
  2. temperatureto cool
  3. customthe solid that crystallized
  4. filtrationwas filtered off
  5. washwashed
  6. customdried in vacuo

Sources & evidence

ORD record
ord-2eda95b982704fe28d29f0686bd463f2
Source dataset
uspto-grants-1997_12
Patent number
US05693657

Reaction notes

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