HRID1938928

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID38042

10-Undecenoyl chloride

C11H19ClO

HCID62493

2,2-Dimethylpropanoyl chloride

C5H9ClO

结构：CC(O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C

HCID22862566

未命名化合物

结构：CC(O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C

HCID22870648

未命名化合物

PRODUCTS

生成物

结构：CC(OC(=O)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C

HCID22870631

未命名化合物

PROCEDURE

实验过程

Employing substantially the same procedure as described in Example 6, but substituting 20-hydroxy-5α-4-azapregn-1-ene-3-one and trimethylacetyl chloride for the 20-hydroxy-4-methyl-5a-4-azapregnan-3-one and 10-undecenoyl chloride, respectively, used therein, the title compound was obtained. MS M-1 calculated for C25H39NO3, mw=402.53; observed m/e 401.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3367bd4edf5148e684f58df71718efba
来源数据集: uspto-grants-1997_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05693809
来源说明: uspto-grants-1997_12

反应 SMILES

[OH:1][CH:2]([C@@H:4]1[C@:21]2([CH3:22])[C@H:7]([C@H:8]3[C@H:18]([CH2:19][CH2:20]2)[C@:16]2([CH3:17])[C@H:11]([NH:12][C:13](=[O:23])[CH:14]=[CH:15]2)[CH2:10][CH2:9]3)[CH2:6][CH2:5]1)[CH3:3].[CH3:24][C:25]([CH3:30])([CH3:29])[C:26](Cl)=[O:27].OC([C@@H]1[C@]2(C)[C@H]([C@H]3[C@H](CC2)[C@]2(C)[C@H](N(C)C(=O)CC2)CC3)CC1)C.C(Cl)(=O)CCCCCCCCC=C>>[CH3:24][C:25]([CH3:30])([CH3:29])[C:26]([O:1][CH:2]([C@@H:4]1[C@:21]2([CH3:22])[C@H:7]([C@H:8]3[C@H:18]([CH2:19][CH2:20]2)[C@:16]2([CH3:17])[C@H:11]([NH:12][C:13](=[O:23])[CH:14]=[CH:15]2)[CH2:10][CH2:9]3)[CH2:6][CH2:5]1)[CH3:3])=[O:27]