O-Allylhydroxylamine → HCID 18630364, compound

HRID 1938995Notes

Reaction equation

[Cl:1][C:2]1[C:12]([Cl:13])=[CH:11][CH:10]=[C:9]([Si:14]([CH3:17])([CH3:16])[CH3:15])[C:3]=1[C:4]([NH:6]CC)=[O:5].[CH2:18]([O:21]N)[CH:19]=[CH2:20]>>[Cl:1][C:2]1[C:12]([Cl:13])=[CH:11][CH:10]=[C:9]([Si:14]([CH3:15])([CH3:16])[CH3:17])[C:3]=1[C:4]([NH:6][O:21][CH2:18][CH:19]=[CH2:20])=[O:5]

Participants

Reactant 2

HCID 420841O-Allylhydroxylamine

HCID 18630184HCID 18630184, compound

Product 1

HCID 18630364HCID 18630364, compoundYield 86%

Procedure

The acid prepared in Example 203 was converted to the acid chloride by the procedure of example b. The acid chloride was reacted with aq O-allylhydroxylamine using General Method E1 to afford the title compound. Purification by recrystallization from ether/hexanes gave 0.68 g of the title compound as a white solid in 86% yield. m.p. 92°-94° C.

Sources & evidence

ORD record: ord-ba582863836e4775a3974a86732b36de
Source dataset: uspto-grants-1997_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05693667

Reaction notes

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